"Administration of pomegranate extract (juice and seed extract) for 2 weeks to ovariectomized mice prevented the loss of uterus weight and shortened the immobility time compared with 5% glucose-dosed mice (control). In addition, ovariectomy-induced decrease of BMD was normalized by administration of the pomegranate extract."Despite the powerful estrogenic properties of pomegranate, this amazing fruit does not exhibit well-known carcinogenic potential associated with synthetic, horse-derived (e.g. Premarin), and even so-called bio-identical or "plant-derived" estrogens. To the contrary, pomegranate has been shown to act selectively to modulate estrogen receptors (SERM) that are beneficial to the organism, while down-regulating activity at the receptors known to be associated with estrogen-sensitive cancers. This type of dynamic intelligence is unique to natural substances, and is not yet reproducible through pharmaceutical preparations. In an August 2011 study published in the Journal of Nutritional Biochemistry, pomegranate extract was compared to the drugs Tamoxifen (T) and Estradiol (E) and was shown to prevent activity associated with estrogen-dependent cancer promotion, without increasing the weight of the uterus, a well known indicator of the potential carcinogenicity of T and E:
"In conclusion, our findings suggest that PME [Pomegranate extract] displays a SERM profile and may have the potential for prevention of estrogen-dependent breast cancers with beneficial effects in other hormone-dependent tissues."In other words, pomegranate is not only non-carcinogenic but is a powerful anti-cancer agent. The GreenMedInfo database now contains 12 studies on its experimentally-confirmed potential to suppress Breast, Prostate, Colorectal, Gastric and Uterine Cancers. GreenMedInfo also contains research on Pomegranate's therapeutic relevance in 77 disease categories.
Hormone replacement, by principle, is capable of feeding the underlying deficiency due to the well-known 'negative feedback loop' within the endocrine system, and may also result in the downstream accumulation of unhealthy levels of hormone metabolites. While it should be regarded as a powerful therapy with significant potential health benefits, it is not without adverse, unintended consequences.
The change of life that attends the normal aging process, despite conventional medical classifications, is not a disease. When the burden of hormone production in women shifts away from the ovary (either via age, stress or medical necessity, e.g. full hysterectomy) to the adrenal cortex, the body can be supported to produce additional hormones via basic nutrients and secretagogues, as well through the ingestion of phytocompounds which mimic hormones, e.g. phytoestrogens, but do not have the health risks associated with endogenously produced hormones. Also, it is possible to regenerate steroid hormones that have undergone transformation into inactive or harmful metabolites via electron donors such as vitamin C.
Read more at: GreenMedInfo.com
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